Feeling overstimulated,
drained, anxious

You might need B1 – your nervous system depends on it to stay regulated and balanced.

Without enough B1, your brain can't properly produce acetylcholine and GABA — the neurotransmitters behind calm, focus, and emotional stability.

4.9 STARS · 200+ VERIFIED BUYERS
Health By Principle B1 Supplement
TTFD
Bioavailable Form
100
Day Supply
ZERO
Sweeteners
50mg
Per Capsule
Why you should try
our B1 with TTFD:
Calming an overactive stress response Clearer thinking, less brain fog Supporting steady, regulated mood Feeling more grounded, less overwhelmed

When your nervous system is off, it can feel like stress, fatigue, or constant overstimulation.

Why? When your nervous system can't regulate itself, those feelings aren't just stress, they're often a sign that the neurotransmitters behind calm and focus aren't being produced efficiently. B1 is essential to making them. Most people aren't getting enough of the right form to feel the difference.

Health By Principle's B1 uses TTFD, a fat-soluble form of thiamine that crosses the blood-brain barrier and reaches the neurological tissue where those neurotransmitters are made.

What your nervous system actually needs to function: B1

Three essential roles B1 plays in nervous system regulation
01

It calms overactive stress signals

B1 is required to produce GABA, the neurotransmitter that tells your nervous system to slow down. When B1 is low, that signal weakens. Stress responses become harder to regulate. Anxiety feels bigger than it should.

TTFD helps deliver B1 where that signal is generated.

02

It powers neurotransmitter production

Your nervous system runs on acetylcholine and GABA, chemicals that require B1 to be made. Without enough, production slows and nerve communication degrades, showing up as irritability, poor focus, and emotional dysregulation.

Without enough B1, the chemicals that keep you calm can't be made.

03

It fuels the neurons themselves

Every neuron depends on mitochondria for energy. B1 is a required cofactor for mitochondrial ATP production. When levels are low, neurons run inefficiently, contributing to mental fatigue, brain fog, and poor stress tolerance.

This is why low B1 is so often associated with chronic stress and burnout.

What's inside and why.

ACTIVE INGREDIENT

TTFD Thiamine

Fat-soluble B1 derivative. Crosses the blood-brain barrier to support neurological function, mitochondrial energy, and cognitive health.

METHYLATION SUPPORT

Methylfolate (B9)

The bioactive form of folate, bypasses the MTHFR conversion step, supporting DNA repair, cellular health, and nervous system function.

ABSORPTION COFACTOR

Vitamin C

Ascorbate improves thiamine uptake and provides neuroprotective antioxidant support, helping maintain cerebral redox balance.

WHAT'S NOT IN IT

No stevia. No artificial sweeteners. No harmful fillers or artificial colors. Built for people who need a clean formula.

Real routines. Real results.

★★★★★

“This is a great supplement. I feel so much more calm since I've been taking it. It does not have the garlic taste that I get with the other B1 supplements.”

Verified Buyer – Laurel B.
★★★★★

“We all need this, but migraine sufferers need it even more. Thank you for providing exactly what is needed.”

Verified Buyer – Gayle S.
★★★★★

“I definitely noticed a big difference when starting with this supplement. I just feel less anxious and my brain seems to feel quieter… I know this supplement works.”

Verified Buyer – Chrissy D.
“First of its kind — formulated specifically around what the research actually shows about how thiamine works in the brain.”
— Dr. Angela Stanton, Neuroscientist & Creator of the Stanton Migraine Protocol

We made it different on purpose

NO ARTIFICIAL COLORS GMP CERTIFIED MADE IN THE USA VEGAN
TTFD

Highest bioavailability form

Fat-soluble, crosses the blood-brain barrier. Not the cheap HCl form used by most brands.

100

Capsules per bottle

100 day supply at 1 capsule daily. More than 3× the supply of most competitors at a comparable price.

USA

GMP certified facility

Formulated, bottled, and third-party tested in an FDA-registered, GMP-certified US lab.

B1 TTFD, B12, or B Complex? What actually supports the nervous system?

Most people have tried B12 or a B complex for anxiety, stress, or fatigue and felt underwhelmed. Here's why and what makes B1 TTFD different for nervous system support specifically.
FEATURE B1 (TTFD) B12 B COMPLEX
What it does Delivers thiamine directly to the brain to fuel neurological energy production Supports nerve integrity, myelin maintenance, red blood cell formation, and methylation General B vitamin coverage, diluted across 8 cofactors
Primary role ATP production in the brain, where thiamine demand is highest Nerve maintenance, oxygen transport, and methylation Cofactor support across multiple body systems
Who it's for Anyone with high neurological demand, stress, or suspected thiamine insufficiency Those with low B12 intake or absorption challenges (common in plant-based diets) Those wanting a general B vitamin safety net without a specific deficiency concern
Brain & nervous system Crosses the blood-brain barrier passively, no transporter needed, unlike standard thiamine Supports myelin and nerve signaling Indirect, broad support, not optimized for neurological needs

Give your nervous system what it's
been missing.

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