News filter by mitochondrial DNA

Mitochondria, often called the “powerhouses” of cells, play a crucial role in brain energy and mental health. When mitochondria fail to meet energy demands, neurons may struggle to communicate effectively, potentially contributing to depression and other mood disorders. Research links mitochondrial dysfunction and stress to DNA leakage, inflammation, and worsening depressive symptoms. Studies show that elevated mitochondrial DNA levels in the blood are tied to stress responses and treatment-resistant depression. This growing evidence suggests mitochondria may be a key factor connecting stress, inflammation, and mood, offering new insights into understanding and treating depression.