Migraine and depression are deeply intertwined partly thanks to similar pathways within the brain. Even though they are distinct conditions - migraines being a neurological disorder and depression a mood disorder - they are so connected that they can both have an impact on each other.
Mental fatigue is a particular and multifaceted challenge for migraine sufferers. Studies have found that mental fatigue contributes to migraines, migraines contribute to mental fatigue, and both contribute to depression.